Study Shows Drop in Efficacy of Pfizer-BioNTech Vaccine as Delta Variant Spreads

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Study Shows Drop in Efficacy of Pfizer-BioNTech Vaccine as Delta Variant Spreads

Israel has recorded a steep drop in the efficacy rate of the Pfizer Inc.-BioNTech SE in preventing coronavirus infections, due to the spread of the delta variant and the easing of government restrictions, Ynet news website reported, citing Health Ministry data.

At the same time, the decline in protection against serious cases and hospitalization is considerably milder, the website said. There was no immediate comment from the ministry.

The figures show that between May 2 and June 5, the vaccine had a 94.3% efficacy rate. From June 6, five days after the government canceled coronavirus restrictions, until early July, the rate plunged to 64%. A similar decline was recorded in protection against coronavirus symptoms, the report said.

At the same time, protection against hospitalization and serious illness remained strong. From May 2 to June 5, the efficacy rate in preventing hospitalization was 98.2%, compared with 93% from June 6 to July 3. A similar decline in the rate was recorded for the vaccine’s efficiency in preventing serious illness among people who had been inoculated.

These figures are in line with ministry data that show that many of the new cases are among people who have been vaccinated, while the number of serious cases is rising much more slowly, Ynet said. Last Friday, 55% of the newly infected had been vaccinated, the website said. As of July 4, there were 35 serious cases of coronavirus in Israel, compared with 21 on June 19.

The government is considering reinstating additional coronavirus-related restrictions after restoring a mandate to wear masks indoors in public spaces. Officials are also discussing whether to recommend a third dose of vaccine, the report said.

Pfizer CEO Albert Bourla has said people will “likely” need a third dose of a Covid-19 vaccine within 12 months of getting fully vaccinated.

Israel had one of the world’s most effective coronavirus inoculation drives. Some 57% of the general population is fully vaccinated, including 88% of the population above the age of 50 -- the group considered most at risk for serious cases.

 

Source: Bloomberg